Fig. 1 · Structure

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CYP1B1-IN-9

Cat. No. A69916 CAS 3077254-39-5

CYP1B1 Inhibitor

CYP1B1-IN-9 is a highly selective competitive inhibitor of CYP1B1, demonstrating an IC50 of 1.48 nM. It effectively inhibits the migration and invasion of A549/T cells and has been shown to resensitize cells resistant to Paclitaxel. Notable for its favorable pharmacokinetic properties, metabolic stability, and safety profile, CYP1B1-IN-9 serves as a valuable tool for investigating tumor-drug resistance mechanisms in cancer research.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3077254-39-5
Applications CYP1B1 Inhibitor
Formula C16H9Cl3N2OS
Molecular Weight 383.68
SMILES
O=C(C1=NC(C2=CC=CC(Cl)=C2)=CS1)NC3=CC(Cl)=CC(Cl)=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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