Fig. 1 · Structure
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CYP1B1 ligand 3
Cat. No.
A69751
CAS
65823-65-6
CYP1B1 Inhibitor
CYP1B1 ligand 3 is a selective inhibitor of the cytochrome P450 enzyme CYP1B1, exhibiting an IC50 of 11.9 nM. This compound is significant for research involving the modulation of CYP1B1 activity and serves as a valuable tool in the development of PROTAC CYP1B1 degrader-2. Its inhibitory properties make it suitable for studies related to drug metabolism and potential therapeutic applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 65823-65-6 |
| Applications | CYP1B1 Inhibitor |
| Formula | C18H12ClN3S2 |
| Molecular Weight | 369.89 |
| SMILES | ClC1=CC=C(NC2=NC(C3=NC(C4=CC=CC=C4)=CS3)=CS2)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.