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CYP3A4-IN-5

Lm PTR1 Inhibitor

CYP3A4-IN-5 is a potent inhibitor of Leishmania major pteridine reductase 1 (Lm PTR1), with an IC50 value of 12.77 µM. This compound is significant for studies focused on the mechanisms of parasite infection and may facilitate the development of therapeutic strategies against leishmaniasis. Its specificity for Lm PTR1 makes it a valuable tool for biochemical and pharmacological research in infectious disease.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	70619-09-9
Applications	Lm PTR1 Inhibitor
Formula	C₁₃H₁₁FN₄S
Molecular Weight	274.32
SMILES	S=C(N/N=C/C1=CC=C(F)C=C1)NC2=CC=CN=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.