Fig. 1 · Structure

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CYP51-IN-15

Cat. No. A52911 CAS 3034186-60-9

CYP51 Inhibitor

CYP51-IN-15 is a selective inhibitor of CYP51, targeting the enzyme in Naegleria fowleri. With an EC50 value of 1.5 μM, it demonstrates potent biological activity against this pathogenic organism. This compound is valuable in research aimed at elucidating mechanisms of action and developing therapeutic strategies against Naegleria fowleri infections.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3034186-60-9
Applications CYP51 Inhibitor
Formula C19H15Cl2F3N2O
Molecular Weight 415.24
SMILES
FC(C1=CC(CO[C@@H](C2=CC=C(Cl)C=C2Cl)CN3C=CN=C3)=CC=C1)(F)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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