Cyslopentenyl cytosine triphosphoric

Catalog No.: A38663
Drug Metabolite
Cyslopentenyl cytosine triphosphoric is a bioactive metabolite of the nucleoside analogue cyclopentenyl cytosine (CPEC) that primarily targets CTP synthetase. This compound effectively inhibits CTP synthetase activity, leading to a depletion of cytidine nucleotide pools. Cyslopentenyl cytosine triphosphoric is essential for research into cancer biology, particularly in the study of leukemia and other related malignancies.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCyslopentenyl cytosine triphosphoric is a bioactive metabolite of the nucleoside analogue cyclopentenyl cytosine (CPEC) that primarily targets CTP synthetase. This compound effectively inhibits CTP synthetase activity, leading to a depletion of cytidine nucleotide pools. Cyslopentenyl cytosine triphosphoric is essential for research into cancer biology, particularly in the study of leukemia and other related malignancies.
Product Information
Catalog NumA38663
FormulaC10H15N2O14P3
Molecular Weight480.15
CAS Number135727-54-7
SMILESO[C@H]1[C@H](N2C(NC(C=C2)=O)=O)C=C([C@H]1O)COP(OP(OP(O)(O)=O)(O)=O)(O)=O
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