CZC-25146 hydrochloride

Catalog No.: A13448

LRRK2 inhibitor

CZC-25146 hydrochloride

CZC-25146 hydrochloride Chemical Structure

CAS NO. 1330003-04-7

CZC-25146 is a potent and selective LRRK2 inhibitor. CZC-25146 prevents mutant LRRK2-induced injury of cultured rodent and human neurons with mid-nanomolar potency.

Availability: In stock

Package Price Qty
5 mg
$80.00
10 mg
$140.00
25 mg
$280.00
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Biological Activity

CZC-25146 is a potent and selective LRRK2 inhibitor. CZC-25146 prevents mutant LRRK2-induced injury of cultured rodent and human neurons with mid-nanomolar potency.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.05 mL 95.24 mL 190.48 mL
0.5 mM 3.81 mL 19.05 mL 38.1 mL
1 mM 1.9 mL 9.52 mL 19.05 mL
5 mM 0.38 mL 1.9 mL 3.81 mL

*The above data is based on the productmolecular weight 525.00. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13448
Actions Inhibitor
CAS No. 1330003-04-7
Formula C22H25FN6O4S.HCl
M. Wt 525.00
Purity >98%
Synonyms CZC-25146, CZC 25146, CZC25146
SMILES COC1=C(C=CC(=C1)N2CCOCC2)NC3=NC=C(C(=N3)NC4=CC=CC=C4NS(=O)(=O)C)F.Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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