CZC54252 hydrochloride

Catalog No.: A15510

LRRK2 inhibitor

CZC54252 hydrochloride

CZC54252 hydrochloride Chemical Structure

CAS NO. 1191911-27-9

CZC-54252 is a potent inhibitor of LRRK2 with IC50s of 1.28 nM and 1.85 nM for wild-type and G2019S LRRK2 respectively.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $180.00

Special Price $162.00

25 mg

Regular Price: $350.00

Special Price $315.00

50 mg

Regular Price: $620.00

Special Price $558.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

CZC-54252 is a potent inhibitor of LRRK2 with IC50s of 1.28 nM and 1.85 nM for wild-type and G2019S LRRK2 respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.47 mL 92.34 mL 184.69 mL
0.5 mM 3.69 mL 18.47 mL 36.94 mL
1 mM 1.85 mL 9.23 mL 18.47 mL
5 mM 0.37 mL 1.85 mL 3.69 mL

*The above data is based on the productmolecular weight 541.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A15510
Actions Inhibitor
M. Wt 541.45
Formula C22H25ClN6O4S.HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1191911-27-9
Synonyms CZC-54252 hydrochloride, CZC 54252 hydrochloride
SMILES COC1=C(C=CC(=C1)N2CCOCC2)NC3=NC=C(C(=N3)NC4=CC=CC=C4NS(=O)(=O)C)Cl.Cl

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