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CZL-046

Epigenetic Reader Domain Inhibitor

CZL-046 is an epigenetic reader domain inhibitor that selectively targets the p300 bromodomain. It effectively modulates histone acetylation, influencing gene expression and cellular signaling pathways. This compound is primarily utilized in research focused on epigenetic regulation and potential therapeutic applications in cancer and other diseases linked to aberrant epigenetic modifications.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3032444-02-0
Applications	Epigenetic Reader Domain Inhibitor
Formula	C₂₉H₂₆D₃F₃N₄O₃
Molecular Weight	541.58
SMILES	O=C1N([C@@H](C[C@@H]1F)C2=NC3=CC(C4=C(ON=C4C)C)=CC=C3N2[C@H]5CC[C@@H](CC5)OC([2H])([2H])[2H])C6=CC(F)=C(C=C6)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.