Fig. 1 · Structure
Documents & Downloads
D-473
Transporter Inhibitor
D-473 is a transporter inhibitor with a primary mechanism of selectively inhibiting serotonin, dopamine, and norepinephrine transporters. This compound is notable for enhancing extracellular levels of these neurotransmitters in rat brain regions, demonstrating significant antidepressant-like activity without inducing motor activation. D-473 is utilized extensively in research related to major depressive disorder, providing valuable insights into therapeutic approaches for mood disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1632000-05-5 |
| Applications | Transporter Inhibitor |
| Formula | C26H27F2NO3 |
| Molecular Weight | 439.49 |
| SMILES | O[C@@H]([C@@H](CO1)NCC2=CC=C(C=C2)OC)C[C@H]1C(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.