Fig. 1 · Structure

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(D-Ala2)-GRF (1-29) amide (human)

GRF Superagonist

(D-Ala2)-GRF (1-29) amide (human) is a superagonist of Growth Hormone-Releasing Factor (GRF), demonstrating approximately 50 times the GH-releasing potency compared to GRF (1-29) in both pig and rat models. This compound is essential for studies focused on growth hormone modulation, metabolic research, and endocrine system regulation. Its enhanced activity makes it a valuable tool for exploring the physiological roles of growth hormone in various biological processes.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 89453-59-8
Applications GRF Superagonist
Formula C149H246N44O42S
Molecular Weight 3357.88
SMILES
[C@@H](CC1=CC=CC=C1)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](NC([C@H](CC2=CC=C(O)C=C2)N)=O)C)=O)CC(O)=O)=O)C)=O)[C@H](CC)C)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(N)=O)=O)CO)=O)CCSC)=O)[C@H](CC)C)=O)CC(O)=O)=O)CCC(N)=O)=O)CC(C)C)=O)CC(C)C)=O)CCCCN)=O)CCCNC(=N)N)=O)C)=O)CO)=O)CC(C)C)=O)CCC(N)=O)=O)=O)CC(C)C)=O)[C@@H](C)C)=O)CCCCN)=O)CCCNC(=N)N)=O)=O)CO)=O)CC(N)=O)=O)[C@@H](C)O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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