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(D-Ala2)-GRF (1-29) amide (human)

Catalog No.: A60549
GRF Superagonist
(D-Ala2)-GRF (1-29) amide (human) is a superagonist of Growth Hormone-Releasing Factor (GRF), demonstrating approximately 50 times the GH-releasing potency compared to GRF (1-29) in both pig and rat models. This compound is essential for studies focused on growth hormone modulation, metabolic research, and endocrine system regulation. Its enhanced activity makes it a valuable tool for exploring the physiological roles of growth hormone in various biological processes.
(D-Ala2)-GRF (1-29) amide (human) 89453-59-8 GRF Superagonist
Grouped product items
Size Price Stock Qty
500µg
$230.00
In stock
1mg
$360.00
In stock
5mg
$810.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(D-Ala2)-GRF (1-29) amide (human) is a superagonist of Growth Hormone-Releasing Factor (GRF), demonstrating approximately 50 times the GH-releasing potency compared to GRF (1-29) in both pig and rat models. This compound is essential for studies focused on growth hormone modulation, metabolic research, and endocrine system regulation. Its enhanced activity makes it a valuable tool for exploring the physiological roles of growth hormone in various biological processes.
Product Information
Catalog NumA60549
FormulaC149H246N44O42S
Molecular Weight3357.88
CAS Number89453-59-8
SequenceTyr-{d-Ala}-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2
Sequence shorteningY-{d-Ala}-DAIFTNSYRKVLGQLSARKLLQDIMSR-NH2
SMILES[C@@H](CC1=CC=CC=C1)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](NC([C@H](CC2=CC=C(O)C=C2)N)=O)C)=O)CC(O)=O)=O)C)=O)[C@H](CC)C)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(N)=O)=O)CO)=O)CCSC)=O)[C@H](CC)C)=O)CC(O)=O)=O)CCC(N)=O)=O)CC(C)C)=O)CC(C)C)=O)CCCCN)=O)CCCNC(=N)N)=O)C)=O)CO)=O)CC(C)C)=O)CCC(N)=O)=O)=O)CC(C)C)=O)[C@@H](C)C)=O)CCCCN)=O)CCCNC(=N)N)=O)=O)CO)=O)CC(N)=O)=O)[C@@H](C)O)=O
Useful Calculator

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GPCR/G Protein > GHSR