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D-AP7

iGluR

D-AP7 is a selective antagonist of the NMDA receptor, primarily targeting ionotropic glutamate receptors (iGluRs). It demonstrates inhibitory effects on epileptiform activity, significantly reducing the duration and frequency of exogenously induced neuronal bursts. Additionally, D-AP7 enhances the amplitude of secondary action potentials, potentially aiding in the restoration of neuronal function during epileptiform episodes. Furthermore, it has been observed to induce anxiogenic effects and impair memory consolidation in passive avoidance learning paradigms, making it relevant for studies investigating neuropharmacology and epilepsy.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	81338-23-0
Applications	iGluR
Formula	C₇H₁₆NO₅P
Molecular Weight	225.18
SMILES	OC([C@H](N)CCCCCP(O)(O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.