Fig. 1 · Structure
Documents & Downloads
D-Arabinose-13C-1
Stable Isotope
D-Arabinose-13C-1 is a stable isotope-labeled form of D-Arabinose. This compound serves as an orally active antidepressant and demonstrates significant growth inhibition of C. elegans, with an IC50 value of 7.5 mM. D-Arabinose-13C-1 can cross the blood-brain barrier, selectively modulating the metabolism of D-ribose and D-fructose, while also inhibiting cell biofilm synthesis and exhibiting antibacterial properties. Its mechanism involves activating the ACSS2-PPARγ/TFEB-CRTC1 axis, influencing CRTC1 transcription through the lysosomal AXIN-LKB1-AMPK pathway, which underlies its antidepressant-like effects.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 139657-60-6 |
| Applications | Stable Isotope |
| Formula | C413CH10O5 |
| Molecular Weight | 151.12 |
| SMILES | O[13CH2][C@@H](O)[C@@H](O)[C@H](O)C=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.