Fig. 1 · Structure

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D-Arabinose-d2

Stable Isotope

D-Arabinose-d2 is a deuterated form of D-Arabinose, functioning as a stable isotope. This compound exhibits oral antidepressant properties and acts as a growth inhibitor for *Caenorhabditis elegans* with an IC50 value of 7.5 mM. D-Arabinose-d2 is capable of crossing the blood-brain barrier, selectively disrupting the metabolism of D-ribose and D-fructose, and inhibiting nematode growth. Additionally, it has antibacterial activity by disrupting cell biofilm synthesis and activates the ACSS2-PPARγ/TFEB-CRTC1 signaling axis via the lysosomal AXIN-LKB1-AMPK pathway, thereby promoting CRTC1 transcription and an antidepressant-like effect.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2419933-20-1
Applications Stable Isotope
Formula C5H8D2O5
Molecular Weight 152.14
SMILES
O=C[C@H]([C@@H]([C@@H](C([2H])([2H])O)O)O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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