Fig. 1 · Structure

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(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P acetate

Substance P/Bombesin Antagonist

(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P acetate is a selective antagonist for Substance P and Bombesin receptors. This compound effectively modulates ocular inflammatory responses triggered by antidromic trigeminal nerve stimulation. It is a valuable tool for research on neurogenic inflammation and pain mechanisms.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 143077-65-0
Applications Substance P/Bombesin Antagonist
Formula C75H108N20O13.xC2H4O2
Molecular Weight 1497.79 (free base)
SMILES
C(C)(O)=O.C([C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](CC=2C=3C(NC2)=CC=CC3)C(N[C@H](C(N[C@@H](CC(C)C)C(N)=O)=O)CC(C)C)=O)=O)=O)NC([C@@H](NC([C@@H](NC(=O)[C@H]4N(C([C@@H](NC(=O)[C@@H]5N(C([C@@H](CCCNC(=N)N)N)=O)CCC5)CCCCN)=O)CCC4)CCC(N)=O)=O)CCC(N)=O)=O)C=6C=7C(NC6)=CC=CC7

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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