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D-Boc Valine methyl ester

Intermediate

D-Boc Valine methyl ester is an intermediate used in the synthesis of Taltobulin, a potent tubulin inhibitor. Taltobulin disrupts tubulin polymerization, leading to mitotic arrest and subsequent apoptosis. This compound is essential for the development of antibody-drug conjugates (ADCs), particularly in the context of cytotoxic applications in cancer research.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	106391-85-9
Applications	Intermediate
Formula	C₁₁H₂₁NO₄
Molecular Weight	231.29
SMILES	O=C(OC)[C@@H](C(C)C)NC(OC(C)(C)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.