Fig. 1 · Structure

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(d(CH2)51,Tyr(Me)2,Dab5,Arg8)-Vasopressin

V1aR Antagonist

(d(CH2)51,Tyr(Me)2,Dab5,Arg8)-Vasopressin is a selective antagonist of the vasopressin V1a receptor, exhibiting a pA2 value of 6.71. This compound is instrumental in studying vasopressin's role in various physiological processes and pathophysiological conditions. Its specificity makes it a valuable tool for research related to vascular regulation, fluid balance, and associated disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 176714-12-8
Applications V1aR Antagonist
Formula C52H76N14O11S2
Molecular Weight 1137.38
Synonyms d(CH2)5[Tyr(Me)2, Dab5]AVP
SMILES
O=C1CC2(SSC[C@@H](C(=O)N3[C@H](C(N[C@@H](CCCNC(=N)N)C(NCC(N)=O)=O)=O)CCC3)NC(=O)[C@H](CCN)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)[C@H](CC5=CC=C(OC)C=C5)N1)CCCCC2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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