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(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin

Catalog No.: A62798
Oxytocin Receptor Antagonist
(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin is an oxytocin receptor antagonist that effectively inhibits oxytocin-induced enhancement of inhibitory postsynaptic currents in CA1 pyramidal neurons. This compound is valuable for investigating the role of oxytocin in synaptic transmission and neuronal regulation. Researchers can utilize this reagent to explore its potential implications in neurobiology and associated therapeutic applications.
(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin 115499-13-3 Oxytocin Receptor Antagonist
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Size Price Stock Qty
5mg
$350.00
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10mg
$650.00
In stock
50mg
$2,000.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin is an oxytocin receptor antagonist that effectively inhibits oxytocin-induced enhancement of inhibitory postsynaptic currents in CA1 pyramidal neurons. This compound is valuable for investigating the role of oxytocin in synaptic transmission and neuronal regulation. Researchers can utilize this reagent to explore its potential implications in neurobiology and associated therapeutic applications.
Product Information
Catalog NumA62798
FormulaC45H69N9O12S2
Molecular Weight992.21
CAS Number115499-13-3
Sequence{β-Mercapto-β,β-cyclopentamethylene-propionyl}-{Tyr(Me)}-Ile-Thr-Asn-Cys-Pro-{Orn} (Disulfide bridge: Mpa1-Cys6)
Sequence shortening{β-Mercapto-β,β-cyclopentamethylene-propionyl}-{Tyr(Me)}-ITNCP-{Orn} (Disulfide bridge: Mpa1-Cys6)
SMILES[H][C@]1(NC(=O)[C@@]([H])(NC(=O)[C@H](Cc2ccc(OC)cc2)NC(=O)CC2(CCCCC2)SSC[C@H](NC(=O)[C@H](CC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN)C(O)=O)[C@@H](C)CC)[C@@H](C)O
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GPCR/G Protein > Oxytocin Receptor