D-Cl-amidine

Catalog No.: A31562
PAD1 Inhibitor
D-Cl-amidine is a selective inhibitor of the peptidylarginine deiminase 1 (PAD1) enzyme. It exhibits significant biological activity in modulating citrullination processes involved in various physiological and pathological conditions. This reagent is primarily utilized in research applications focusing on inflammatory diseases, neurodegeneration, and cancer biology, providing essential insights into the role of PAD1 in cellular functions. D-Cl-amidine demonstrates a favorable toxicity profile, supporting its use in experimental settings.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionD-Cl-amidine is a selective inhibitor of the peptidylarginine deiminase 1 (PAD1) enzyme. It exhibits significant biological activity in modulating citrullination processes involved in various physiological and pathological conditions. This reagent is primarily utilized in research applications focusing on inflammatory diseases, neurodegeneration, and cancer biology, providing essential insights into the role of PAD1 in cellular functions. D-Cl-amidine demonstrates a favorable toxicity profile, supporting its use in experimental settings.
Product Information
Catalog NumA31562
FormulaC14H19ClN4O2
Molecular Weight310.78
CAS Number1404060-15-6
SMILESO=C(N[C@@H](C(N)=O)CCCNC(CCl)=N)C1=CC=CC=C1
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