Fig. 1 · Structure
Documents & Downloads
D-Dopa
GCPII Inhibitor
D-Dopa (3-Hydroxy-D-tyrosine) is a potent, non-competitive allosteric inhibitor of glutamate carboxypeptidase II (GCPII), demonstrating an IC50 of 200 nM. This compound is known to elevate brain dopamine levels and induce turning behavior in rat models. Additionally, D-Dopa shows inhibitory effects against severe fever with thrombocytopenia syndrome (SFTS) virus infection. It serves as a valuable reagent for research applications in neurological diseases and viral infections.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 5796-17-8 |
| Applications | GCPII Inhibitor |
| Formula | C9H11NO4 |
| Molecular Weight | 197.19 |
| Synonyms | 3-Hydroxy-D-tyrosine |
| SMILES | N[C@H](Cc1ccc(O)c(O)c1)C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.