Fig. 1 · Structure
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D-erythro-MAPP
Ceramidase Inhibitor
D-erythro-MAPP is a potent ceramidase inhibitor, exhibiting an IC50 value between 1-5 μM in vitro. By selectively targeting ceramidase, it plays a crucial role in modulating ceramide metabolism. This compound is valuable for investigating the implications of ceramide signaling in various biological processes, including apoptosis and inflammation, making it a useful tool for researchers studying lipid metabolism and related diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 143492-38-0 |
| Applications | Ceramidase Inhibitor |
| Formula | C23H39NO2 |
| Molecular Weight | 361.56 |
| Synonyms | D-e-MAPP |
| SMILES | O[C@@H](C1=CC=CC=C1)[C@@H](C)NC(CCCCCCCCCCCCC)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.