Fig. 1 · Structure

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D-G23

RAD52 Inhibitor

D-G23 is a selective inhibitor of RAD52, which plays a critical role in DNA repair mechanisms. By disrupting RAD52-mediated pathways, D-G23 effectively suppresses the proliferation of BRCA1- and BRCA2-deficient cancer cells. This compound is particularly relevant for research involving homologous recombination-related cancers, including hereditary breast and ovarian cancers associated with BRCA1 and BRCA2 mutations.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1225141-73-0
Applications RAD52 Inhibitor
Formula C19H22N4O3
Molecular Weight 354.40
SMILES
OCCCNC1=C2C=CC=CC2=NC(NC3=CC(OC)=CC=C3OC)=N1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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