Fig. 1 · Structure
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D(+)-Galactosamine hydrochloride
Acute Liver Injury Inducer
D(+)-Galactosamine hydrochloride is a well-characterized experimental toxin that primarily induces acute liver injury through the generation of reactive oxygen species and depletion of uridine triphosphate (UTP) nucleotides. Its administration can also lead to renal dysfunction, making renal failure a potential complication during the progression of liver damage. This compound is commonly utilized in animal models, particularly in studies involving lipopolysaccharide/D(+)-galactosamine-induced acute liver injury, serving as a relevant model for investigating fulminant hepatic failure.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inducer |
| CAS Number | 1772-03-8 |
| Applications | Acute Liver Injury Inducer |
| Formula | C6H14ClNO5 |
| Molecular Weight | 215.63 |
| Synonyms | D-Galactosamine HCl |
| SMILES | OC1[C@H](N)[C@@H](O)[C@@H](O)[C@@H](CO)O1.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.