Fig. 1 · Structure
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D-myo-Inositol-1,2,4,5-tetraphosphate tetrasodium salt
Ins(1,4,5)P3 Receptor Agonist
D-myo-Inositol-1,2,4,5-tetraphosphate tetrasodium salt is an Ins(1,4,5)P3 receptor agonist that exhibits a binding affinity with a Ki of 11 nM. This compound activates calcium mobilization, demonstrating an EC50 value of 0.22 μM in CHO cells. It serves as a valuable tool for research in cellular signaling pathways involving inositol phosphates and their role in calcium signal transduction.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 154278-46-3 |
| Applications | Ins(1,4,5)P3 Receptor Agonist |
| Formula | C6H12Na4O18P4 |
| Molecular Weight | 588.00 |
| Synonyms | Ins(1,2,4,5)P4 tetrasodium salt; 1,2,4,5-IP4 tetrasodium salt |
| SMILES | O[C@@H]1[C@H]([C@@H]([C@H]([C@H]([C@H]1OP(O)(O[Na])=O)OP(O)(O[Na])=O)O)OP(O)(O[Na])=O)OP(O)(O[Na])=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.