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D-Phe2,6, Pro3-LH-RH

Catalog No.: A60720
LHRH Antagonist
[D-Phe2,6, Pro3]-LH-RH is a potent luteinizing hormone-releasing hormone (LHRH) antagonist that effectively inhibits the action of LHRH. This compound plays a critical role in regulating reproductive physiology by blocking the secretion of luteinizing hormone and follicle-stimulating hormone. It is widely used in research applications focused on hormone regulation, reproductive biology, and the study of pituitary function.
[D-Phe2,6, Pro3]-LH-RH 64789-67-9 LHRH Antagonist
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Research use only. We do not sell to patients.
Data Sheet SDS Compound Handling Instructions

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description[D-Phe2,6, Pro3]-LH-RH is a potent luteinizing hormone-releasing hormone (LHRH) antagonist that effectively inhibits the action of LHRH. This compound plays a critical role in regulating reproductive physiology by blocking the secretion of luteinizing hormone and follicle-stimulating hormone. It is widely used in research applications focused on hormone regulation, reproductive biology, and the study of pituitary function.
Product Information
Catalog NumA60720
FormulaC59H80N14O13
Molecular Weight1193.35
CAS Number64789-67-9
Sequence shortening{Glp}-{d-Phe}-PSY-{d-Phe}-LRPG-NH2
SMILESC([C@@H](CC1=CC=CC=C1)NC(=O)[C@@H]2CCC(=O)N2)(=O)N3[C@H](C(N[C@H](C(N[C@@H](CC4=CC=C(O)C=C4)C(N[C@H](CC5=CC=CC=C5)C(N[C@H](C(N[C@H](C(=O)N6[C@H](C(NCC(N)=O)=O)CCC6)CCCNC(=N)N)=O)CC(C)C)=O)=O)=O)CO)=O)CCC3
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Endocrinology-Hormones > GnRH receptor