(D-Phe7)-α-MSH

Catalog No.: A61669
α-MSH Analogue
(D-Phe7)-α-MSH is an analogue of α-melanocyte-stimulating hormone (α-MSH), a peptide hormone involved in the regulation of various physiological functions, including pigmentation and appetite control. This compound exhibits biological activity by binding to melanocortin receptors, influencing melanogenesis and potentially modulating inflammatory responses. Research applications include studies on skin pigmentation, obesity, and the role of melanocortin pathways in metabolic processes.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(D-Phe7)-α-MSH is an analogue of α-melanocyte-stimulating hormone (α-MSH), a peptide hormone involved in the regulation of various physiological functions, including pigmentation and appetite control. This compound exhibits biological activity by binding to melanocortin receptors, influencing melanogenesis and potentially modulating inflammatory responses. Research applications include studies on skin pigmentation, obesity, and the role of melanocortin pathways in metabolic processes.
Product Information
Catalog NumA61669
FormulaC77H109N21O19S
Molecular Weight1664.88
CAS Number92937-43-4
Sequence shorteningAc-SYSMEH-{d-Phe}-RWGKPV-NH2
SMILESCSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O
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