Fig. 1 · Structure
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(D-Pro7)-Angiotensin I/II (1-7)
Mas Receptor Inhibitor
(D-Pro7)-Angiotensin I/II (1-7) is a selective Mas receptor inhibitor, demonstrating a Ki of 0.001 μM for rat receptors. It competitively inhibits the binding of Angiotensin-(1-7) to the Mas receptor, effectively reducing the vasodilatory response in rat aortic tissues under both physiological and hypertensive states. This reagent is valuable for investigating the role of the renin-angiotensin system and the underlying mechanisms associated with hypertension.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 586962-44-9 |
| Applications | Mas Receptor Inhibitor |
| Formula | C41H62N12O11 |
| Molecular Weight | 899.00 |
| SMILES | OC(C=C1)=CC=C1C[C@H](NC([C@H](C(C)C)NC([C@H](CCCNC(N)=N)NC([C@@H](N)CC(O)=O)=O)=O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC2=CN=CN2)C(N3[C@H](CCC3)C(O)=O)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.