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(D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH

Catalog No.: A60700
LHRH Analogue
(D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH is an analogue of luteinizing hormone-releasing hormone (LHRH) that primarily targets the LHRH receptor. This compound is designed to modulate reproductive hormone release by stimulating the secretion of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH). It serves as a valuable tool in reproductive biology and endocrinology research, particularly in studies related to fertility and hormonal regulation.
(D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH 1926163-38-3 LHRH Analogue
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH is an analogue of luteinizing hormone-releasing hormone (LHRH) that primarily targets the LHRH receptor. This compound is designed to modulate reproductive hormone release by stimulating the secretion of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH). It serves as a valuable tool in reproductive biology and endocrinology research, particularly in studies related to fertility and hormonal regulation.
Product Information
Catalog NumA60700
FormulaC59H84N18O14
Molecular Weight1269.41
CAS Number1926163-38-3
Sequence{Pyr}-His-Trp-Ser-Tyr-{d-Ser(tBu)}-{d-Leu}-Arg-Pro-{Azagly}-NH2
Sequence shortening{Pyr}-HWSY-{d-Ser(tBu)}-{d-Leu}-RP-{Azagly}-NH2
SMILESCC(C)C[C@@H](NC(=O)[C@@H](COC(C)(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)NNC(N)=O
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Endocrinology-Hormones > GnRH receptor