d-T101 peptide

Catalog No.: A25348
T1/ST2 Receptor Ligand
d-T101 peptide is an important ligand for the T1/ST2 receptor, primarily involved in mediating apoptosis through the activation of caspases 3, 8, and 9, along with JNKinase and p38 MAPKinase pathways. This peptide exhibits significant immunostimulatory and anticancer properties by selectively inducing apoptosis in proliferating cancer cells. It enhances the expression of interleukin-2 (IL-2) and interferon-gamma (IFN-γ), as well as promoting the recruitment of natural killer (NK) cells and M1 macrophages to tumor sites. d-T101 peptide is invaluable for research in cancer immunotherapy and the modulation of immune responses.
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptiond-T101 peptide is an important ligand for the T1/ST2 receptor, primarily involved in mediating apoptosis through the activation of caspases 3, 8, and 9, along with JNKinase and p38 MAPKinase pathways. This peptide exhibits significant immunostimulatory and anticancer properties by selectively inducing apoptosis in proliferating cancer cells. It enhances the expression of interleukin-2 (IL-2) and interferon-gamma (IFN-γ), as well as promoting the recruitment of natural killer (NK) cells and M1 macrophages to tumor sites. d-T101 peptide is invaluable for research in cancer immunotherapy and the modulation of immune responses.
Product Information
Catalog NumA25348
FormulaC96H129N21O20
Molecular Weight1897.18
CAS Number2120397-85-3
Sequenced(Trp-Trp-Thr-Phe-Phe-Leu-Pro-Ser-Thr-Leu-Trp-Glu-Arg-Lys)
Sequence shorteningd(WWTFFLPSTLWERK)
SMILESC([C@H](C(N[C@@H](C(N[C@@H](C(N[C@H](CCCCN)C(O)=O)=O)CCCNC(=N)N)=O)CCC(O)=O)=O)NC([C@H](NC([C@H](NC([C@H](NC(=O)[C@@H]1N(C([C@H](NC([C@@H](CC2=CC=CC=C2)NC([C@@H](CC3=CC=CC=C3)NC([C@H](NC([C@@H](CC=4C=5C(NC4)=CC=CC5)NC([C@@H](CC=6C=7C(NC6)=CC=CC7)N)=O)=O)[C@H](C)O)=O)=O)=O)CC(C)C)=O)CCC1)CO)=O)[C@H](C)O)=O)CC(C)C)=O)C=8C=9C(NC8)=CC=CC9
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