D-Trp11-Neurotensin

Catalog No.: A62298
Neurotensin Receptor Modulator
[D-Trp11]-Neurotensin is a neurotensin receptor modulator that acts as a selective antagonist in perfused rat hearts while exhibiting full agonistic activity in guinea pig atria and rat stomach strips. This compound has demonstrated the ability to inhibit neurotensin-induced hypotension, making it a valuable tool for studying neurotensin receptor dynamics and their physiological effects. Its diverse biological activity supports various research applications, including cardiovascular and gastrointestinal studies.
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5mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description[D-Trp11]-Neurotensin is a neurotensin receptor modulator that acts as a selective antagonist in perfused rat hearts while exhibiting full agonistic activity in guinea pig atria and rat stomach strips. This compound has demonstrated the ability to inhibit neurotensin-induced hypotension, making it a valuable tool for studying neurotensin receptor dynamics and their physiological effects. Its diverse biological activity supports various research applications, including cardiovascular and gastrointestinal studies.
Product Information
Catalog NumA62298
FormulaC80H122N22O19
Molecular Weight1695.96
CAS Number73634-68-1
Sequence{Pyr}-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-{D-Trp}-Ile-Leu
Sequence shortening{Pyr}-LYENKPRRP-{D-Trp}-IL
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