[D-Trp8]-γ-MSH is a selective agonist of the melanocortin 3 (MC3) receptor, exhibiting an IC50 of 6.7 nM in CHO cells. This compound also demonstrates activity against the MC4 and MC5 receptors, with IC50 values of 600 nM and 340 nM, respectively. [D-Trp8]-γ-MSH is implicated in research applications related to inflammatory disorders, showing potential neuroprotective effects in conditions such as rheumatoid arthritis and colitis.
[D-Trp8]-γ-MSH is a selective agonist of the melanocortin 3 (MC3) receptor, exhibiting an IC50 of 6.7 nM in CHO cells. This compound also demonstrates activity against the MC4 and MC5 receptors, with IC50 values of 600 nM and 340 nM, respectively. [D-Trp8]-γ-MSH is implicated in research applications related to inflammatory disorders, showing potential neuroprotective effects in conditions such as rheumatoid arthritis and colitis.
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