Fig. 1 · Structure

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D3R ligand 1

D3R Ligand

D3R ligand 1 is a potent and selective antagonist targeting the dopamine receptor D3R, with a Ki value of 66 nM. Utilizing a THPB template, this compound effectively inhibits both G-protein- and β-arrestin-mediated signaling pathways. D3R ligand 1 is valuable for researchers investigating dopamine receptor signaling and its implications in neuropharmacology.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 2983777-91-7
Applications D3R Ligand
Formula C27H37NO5
Molecular Weight 455.59
SMILES
OC1=C(C=C(C2=C1)CCN3[C@H]2CC4=CC=C(C(OCCOCC)=C4C3)O)OCCCCCC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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