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D3R/MOR antagonist 1

D3R/MOR Antagonist

D3R/MOR Antagonist 1, a dual antagonist targeting the D3 receptor and the mu-opioid receptor, exhibits affinities of Ki values at 46.5 nM and 691 nM, respectively. This compound is designed to potentially elicit analgesic effects while minimizing opioid misuse liability through D3R antagonism. Its unique mechanism makes it a valuable tool for research in pain management and substance use disorders.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	3033883-15-4
Applications	D3R/MOR Antagonist
Formula	C₂₂H₂₇Cl₂N₃O
Molecular Weight	420.38
SMILES	ClC1=C(N2CCN(CCC3(C4=NC=CC=C4)CCOCC3)CC2)C=CC=C1Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.