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D3R/MOR antagonist 2

D3R/MOR Antagonist

D3R/MOR antagonist 2 targets the dopamine D3 receptor (D3R) and the mu-opioid receptor (MOR) as a dual antagonist. With affinities of Ki 361 nM for D3R and 85.2 nM for MOR, this compound exhibits potential analgesic effects through MOR partial agonism while simultaneously mitigating opioid misuse liability via D3R antagonism. It serves as a valuable tool for research in pain management and addiction pharmacology.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	3033883-17-6
Applications	D3R/MOR Antagonist
Formula	C₂₅H₃₁ClN₂O
Molecular Weight	410.98
SMILES	ClC1=CC=C(C=C1)[C@H]2[C@@H](C2)NCCC3(C4=NC=CC=C4)CC5(CCCC5)OCC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.