Fig. 1 · Structure
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Δ7(Z)-C14-HSL
Immunosuppressive Agent
Δ7(Z)-C14-HSL is an immunosuppressive agent that inhibits the proliferation of mouse splenic cells, exhibiting an IC50 of 17 μM. This compound offers valuable insights into the molecular mechanisms underlying TNF-R-driven immune disorders, with potential applications in the study of autoimmune diseases such as psoriasis, rheumatoid arthritis, and type 1 diabetes. Researchers may utilize Δ7(Z)-C14-HSL to further explore its therapeutic implications in these conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 482598-46-9 |
| Applications | Immunosuppressive Agent |
| Formula | C18H29NO4 |
| Molecular Weight | 323.43 |
| Synonyms | N-(3-Oxo-7Z-tetradecenoyl)-L-homoserine lactone |
| SMILES | CCCCCC/C=C\CCCC(CC(N[C@@H]1C(OCC1)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.