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DA-302168S

GLP-1R Agonist

DA-302168S is a selective agonist of the glucagon-like peptide-1 receptor (GLP-1R), exhibiting an EC50 value of 1.32 nM. This compound effectively stimulates insulin secretion and demonstrates hypoglycemic effects while decreasing food intake. DA-302168S primarily targets GLP-1R in primates and humans, with minimal activity observed in rodent and canine models. It is a valuable tool for research in type 2 diabetes and obesity.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	2969158-02-7
Applications	GLP-1R Agonist
Formula	C₃₃H₂₄ClF₂N₃O₅
Molecular Weight	616.01
SMILES	O=C(C1=CC2=C(N=C(N2C[C@@H]3CCO3)CC4=CC=C(C=C4F)C5=NC(OCC6=CC=C(C7=C6OC=C7)Cl)=C(C=C5)F)C=C1)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.