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DA-PROTAC

Atox1/CCS PROTAC Degrader

DA-PROTAC is a selective PROTAC degrader targeting the copper ion-transport proteins Atox1 and CCS. By facilitating the recruitment of E3 ligase, DA-PROTAC promotes the ubiquitination and subsequent proteasomal degradation of both Atox1 and CCS. This compound is particularly valuable for research in triple negative breast cancer, allowing for the investigation of copper transport mechanisms and their implications in tumor biology.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Degrader
CAS Number	2488660-12-2
Applications	Atox1/CCS PROTAC Degrader
Formula	C₄₆H₅₀BrF₂N₇O₈S₂
Molecular Weight	1010.96
SMILES	O=C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(N=CS3)C)C=C2)=O)C(C(C)(C)C)NC(COCCCOCC(NC4=C(C(NC5=C(C=C(C=C5F)F)Br)=O)SC6=C4C=C(CCC7)C7=N6)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.