Fig. 1 · Structure
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Dacarbazine citrate
Antineoplastic Agent
Dacarbazine citrate is an antineoplastic alkylating agent that functions as a cell cycle nonspecific drug. It significantly inhibits the proliferation of T and B lymphoblasts, demonstrating IC50 values of 50 and 10 µg/mL, respectively. Dacarbazine citrate is particularly valuable in cancer research, including studies on apoptosis and treatment strategies for conditions such as metastatic malignant melanoma.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 64038-56-8 |
| Applications | Antineoplastic Agent |
| Formula | C12H18N6O8 |
| Molecular Weight | 374.31 |
| Synonyms | Imidazole Carboxamide citrate |
| SMILES | O=C(C1=C(/N=N/N(C)C)NC=N1)N.O=C(CC(C(O)=O)(O)CC(O)=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.