Fig. 1 · Structure
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Dacarbazine hydrochloride
Anticancer Agent
Dacarbazine hydrochloride is a cell cycle nonspecific alkylating agent that targets cancer by inhibiting DNA synthesis. It demonstrates significant activity against T and B lymphoblasts, with IC50 values of 50 and 10 μg/mL, respectively. This compound is primarily utilized in research focused on metastatic malignant melanoma and its therapeutic mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 17925-90-5 |
| Applications | Anticancer Agent |
| Formula | C6H11ClN6O |
| Molecular Weight | 218.64 |
| Synonyms | Imidazole Carboxamide hydrochloride |
| SMILES | O=C(C1=C(/N=N/N(C)C)NC=N1)N.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.