Dalbavancin-d6 is a deuterium-labeled derivative of the semisynthetic lipoglycopeptide antibiotic Dalbavancin. This compound exhibits strong bactericidal activity against Gram-positive bacteria, effectively inhibiting Staphylococcus aureus and Bacillus anthracis, with minimum inhibitory concentrations (MIC90s) of 0.06 μg/mL and 0.25 μg/mL, respectively. Dalbavancin-d6 serves as a valuable stable isotope for metabolic labeling studies and pharmacokinetic research, aiding in the investigation of antibiotic mechanisms and dynamics in biological systems.
Dalbavancin-d6 is a deuterium-labeled derivative of the semisynthetic lipoglycopeptide antibiotic Dalbavancin. This compound exhibits strong bactericidal activity against Gram-positive bacteria, effectively inhibiting Staphylococcus aureus and Bacillus anthracis, with minimum inhibitory concentrations (MIC90s) of 0.06 μg/mL and 0.25 μg/mL, respectively. Dalbavancin-d6 serves as a valuable stable isotope for metabolic labeling studies and pharmacokinetic research, aiding in the investigation of antibiotic mechanisms and dynamics in biological systems.
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