Dalpiciclib isethionate

Catalog No.: A54357
CDK4/6 Inhibitor
Dalpiciclib isethionate is a selective inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6). By inhibiting the kinase activity of these enzymes, Dalpiciclib effectively disrupts the progression of the cell cycle from the G1 phase to the S phase, which reduces abnormal cellular proliferation. This compound is primarily utilized in cancer research, particularly in the study of breast cancer, where CDK4/6 dysregulation plays a critical role in tumor growth.
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Research use only. We do not sell to patients.

Other Forms of Dalpiciclib isethionate

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
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Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
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Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Biological Activity
DescriptionDalpiciclib isethionate is a selective inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6). By inhibiting the kinase activity of these enzymes, Dalpiciclib effectively disrupts the progression of the cell cycle from the G1 phase to the S phase, which reduces abnormal cellular proliferation. This compound is primarily utilized in cancer research, particularly in the study of breast cancer, where CDK4/6 dysregulation plays a critical role in tumor growth.
Product Information
Catalog NumA54357
FormulaC27H36N6O6S
Molecular Weight572.68
CAS Number1980822-14-7
SMILESO=C1C(C(C)=O)=C(C)C2=C(N1C3CCCC3)N=C(NC4=NC=C(C5CCNCC5)C=C4)N=C2.O=S(O)(CCO)=O
SynonymsSHR-6390 isethionate
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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