Fig. 1 · Structure

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Danicamtiv

Cardiac Myosin Activator

Danicamtiv is a selective allosteric activator of cardiac myosin, serving as a cardiac inotropic agent. It enhances cardiac systolic function while maintaining mechanical efficiency, making it a valuable tool for research on heart failure and myocardial contractility. This compound is instrumental in studying the modulation of cardiac contractile function and understanding its implications in cardiovascular diseases.

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Specifications

Manufacturer Adooq Bioscience
Actions Activator
CAS Number 1970972-74-7
Applications Cardiac Myosin Activator
Formula C16H20F3N5O4S
Molecular Weight 435.42
Synonyms MYK-491
SMILES
O=S([C@@](C1CCN(CC1)C(NC2=NOC=C2)=O)(C)F)(C3=CN(N=C3C(F)F)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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