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Dapirolizumab
Dapirolizumab is a monoclonal antibody specifically designed to target and bind to CD40 ligand (CD40L), effectively blocking its interaction with CD40 receptors on the surface of immune cells. This interaction is crucial for the activation of the adaptive immune response. By inhibiting this pathway, Dapirolizumab helps to modulate immune system activity and has been shown to attenuate the symptoms of systemic lupus erythematosus. This antibody is applicable in research focused on the pathogenesis and treatment of autoimmune diseases, particularly those involving aberrant CD40-CD40L signaling.
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Product Details
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1416147-64-2 |
| Molecular Weight | 145500 |
Storage
Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.