Fig. 1 · Structure
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Dasolampanel
Kainate Receptor Antagonist
Dasolampanel is a kainate receptor antagonist that modulates neuronal excitability by inhibiting the activity of kainate receptors, thereby decreasing glutamate-mediated excitatory transmission. This compound is valuable for research into neurological conditions characterized by excessive neuronal activation, including excitability disorders and sleep disturbances. Its role in the regulation of synaptic transmission makes it a significant tool for studying the underlying mechanisms of various excitatory neurotransmission disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 503294-13-1 |
| Applications | Kainate Receptor Antagonist |
| Formula | C18H21ClN4O3 |
| Molecular Weight | 376.84 |
| SMILES | O=C([C@H]1NC[C@]2([H])CC[C@H](OC3=CC=CC(Cl)=C3C4=NN=CN4)C[C@]2([H])C1)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.