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DB28

Catalog No.: A65025
MR1 Ligand
DB28 is an innovative MR1 ligand that functions by competitively inhibiting the activation of mucosal-associated invariant T (MAIT) cells through its interaction with MR1. Additionally, DB28 reduces the cell surface expression of MR1, making it a valuable tool for studies of MAIT cell biology and immune modulation. This compound is applicable in research focused on immune responses and potential therapeutic interventions targeting MR1-related pathways.
DB28 16296-42-7 MR1 Ligand
Grouped product items
Size Price Stock Qty
5mg
$170.00
In stock
10mg
$280.00
In stock
25mg
$510.00
In stock
50mg
$745.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDB28 is an innovative MR1 ligand that functions by competitively inhibiting the activation of mucosal-associated invariant T (MAIT) cells through its interaction with MR1. Additionally, DB28 reduces the cell surface expression of MR1, making it a valuable tool for studies of MAIT cell biology and immune modulation. This compound is applicable in research focused on immune responses and potential therapeutic interventions targeting MR1-related pathways.
Product Information
Catalog NumA65025
FormulaC8H9N3O5
Molecular Weight227.17
CAS Number16296-42-7
SMILESO=C(O)CCNC(C(NC1=O)=CC(N1)=O)=O
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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
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Immunology & Inflammation > MHC