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dBAZ2B

BAZ2B PROTAC Degrader

dBAZ2B is a selective BAZ2B PROTAC degrader with a DC50 of 19 nM. This compound effectively promotes the degradation of the BAZ2B protein, facilitating investigations into protein homeostasis and targeted protein degradation mechanisms. It serves as a valuable tool for research in cellular signaling pathways and potential therapeutic applications in cancer and other diseases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Degrader
CAS Number	3104449-58-0
Applications	BAZ2B PROTAC Degrader
Formula	C₅₅H₆₆FN₁₁O₆S
Molecular Weight	1028.25
SMILES	CC1=C(SC=N1)C2=CC(OC[C@@H]3CC[C@H](CC3)COCC4=NC(C5=CN(N=C5)C)=C(N4CCC6=CN(N=C6)C)C7=CC=C(C=C7)C#N)=C(C=C2)CNC([C@@H]8C[C@H](CN8C([C@H](C(C)(C)C)NC(C9(CC9)F)=O)=O)O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.