dBET6

Catalog No.: A20110
BET degrader
dBET6 is a highly potent, selective and cell-permeable degrader of BET based on PROTAC, with an IC50 of 14 nM, and has antitumor activity.
Grouped product items
Product Name Price Stock Qty
dBET6 5mg
$126.00
In stock
dBET6 10mg
$217.00
In stock
dBET6 50mg
$644.00
In stock
dBET6 100mg
$1,288.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Biological Activity
Discription dBET6 is a highly potent, selective and cell-permeable degrader of BET based on PROTAC, with an IC50 of 14 nM, and has antitumor activity.
Product Information
Catalog Num A20110
Formula C42H45ClN8O7S
Molecular Weight 841.37
CAS Number 1950634-92-0
SMILES O=C(NCCCCCCCCNC(COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)=O)C[C@H]4C5=NN=C(C)N5C6=C(C(C)=C(C)S6)C(C7=CC=C(Cl)C=C7)=N4
Synonyms dBET 6, dBET-6
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 96 mg/mL (114.1 mM)
Water Insoluble
Ethanol 40 mg/mL (47.53 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 11.89 mL 59.43 mL 118.85 mL
0.5 mM 2.38 mL 11.89 mL 23.77 mL
1 mM 1.19 mL 5.94 mL 11.89 mL
5 mM 0.24 mL 1.19 mL 2.38 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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