Fig. 1 · Structure
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DBIBB
GPCR Agonist
DBIBB is a selective agonist for the type 2 G protein-coupled receptor (LPA2), primarily functioning through its interaction with lysophosphatidic acid. This compound has demonstrated the ability to alleviate gastrointestinal radiation syndrome by enhancing intestinal crypt survival and promoting enterocyte proliferation while decreasing apoptosis. DBIBB serves as a promising candidate for research focused on mitigating the effects of acute radiation syndrome, particularly in the hematopoietic and gastrointestinal systems following high-dose γ-radiation exposure.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 1569309-92-7 |
| Applications | GPCR Agonist |
| Formula | C23H20N2O6S |
| Molecular Weight | 452.48 |
| SMILES | O=C(N1CCCCNS(C2=C(C=CC=C2)C(O)=O)(=O)=O)C3=C4C(C=CC=C4C1=O)=CC=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.