DBO-83 dihydrochloride

Catalog No.: A67662
Nicotinic Acetylcholine Receptor Agonist
DBO-83 dihydrochloride is an innovative agonist of the nicotinic acetylcholine receptor (nAChR), exhibiting a high affinity for nAChRs in rat cortical membranes with a Ki value of 4.1 nM. This compound demonstrates significant antinociceptive and anti-amnesic properties, making it a valuable tool for research into pain modulation and cognitive function. Its potential applications in neuroscience and pharmacology make DBO-83 dihydrochloride a critical reagent for studying neuronal signaling pathways and associated disorders.
Grouped product items
Size Price Stock Qty
1mg
$90.00
In stock
5mg
$280.00
In stock
10mg
$460.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDBO-83 dihydrochloride is an innovative agonist of the nicotinic acetylcholine receptor (nAChR), exhibiting a high affinity for nAChRs in rat cortical membranes with a Ki value of 4.1 nM. This compound demonstrates significant antinociceptive and anti-amnesic properties, making it a valuable tool for research into pain modulation and cognitive function. Its potential applications in neuroscience and pharmacology make DBO-83 dihydrochloride a critical reagent for studying neuronal signaling pathways and associated disorders.
Product Information
Catalog NumA67662
FormulaC10H15Cl3N4
Molecular Weight297.61
CAS Number195211-53-1
SMILESClC1=CC=C(N=N1)N2CC(CC3)NC3C2.Cl.Cl
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