Fig. 1 · Structure
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DCAF1 binder 1
Ligands for E3 Ligase
DCAF1 binder 1 is a selective ligand for the CRL4 DCAF1 E3 ligase complex. This compound plays a crucial role in targeted protein degradation (TPD), making it valuable for research applications focused on modulating protein levels and understanding the mechanisms of E3 ligase activity. DCAF1 binder 1 can facilitate investigations into the therapeutic potential of TPD in various disease contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 3053860-67-3 |
| Applications | Ligands for E3 Ligase |
| Formula | C28H35ClN6O |
| Molecular Weight | 507.07 |
| SMILES | NCCNC1=NC(C2(C3=CC=C(C=C3)Cl)CCCCC2)=NC4=C1C=CC(N5CCN(CC5)C(C)=O)=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.