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DCAF1 ligand 1

DCAF1 Ligand

DCAF1 ligand 1 is a specific ligand for DCAF1, a substrate receptor within the cullin-RING ubiquitin ligase complex. This compound is primarily utilized in the synthesis of PROTACs (Proteolysis Targeting Chimeras), particularly in the development of agents like PROTAC BRD4-DCAF1 degrader-1. Its role facilitates targeted protein degradation, making it valuable for research in cellular signaling, cancer biology, and therapeutic development.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	3036941-01-9
Applications	DCAF1 Ligand
Formula	C₂₈H₂₂ClF₂N₃O₃
Molecular Weight	521.94
SMILES	O=C(C1=CC=CC=C1)C2=C(C3=C(C(F)=CC=C3F)C)C(C(N[C@H](C4=CC(Cl)=CC=C4)CC(N)=O)=O)=CN2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.